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Description
Can reducing the dose of a GLP1 receptor agonist during tapering temporarily worsen gastrointestinal side effects such as nausea and diarrhea ? Vision loss due to NAION is a serious but rare side effect of GLP1 medications whether used for management of type 2 diabetes or for weight loss. NAION (non arteritic anterior ischaemic Compound Semaglutide Mom Loses 65 Lbs With GLP 1, Counting Macros, Strength Training Targeting GLP 1, GIP & GCG in Obesity and Type 2 Diabetes Research The metabolite GLP1 (936) is neuroprotective and antiinflammatory in cellular models of neurodegeneration Li 2021 Journal of Neurochemistry Wiley Online Library
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4.8 ★★★★★
Based on 1551 reviews
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Product Reviews
★★★★★ 5
Worthwhile!
Size: Medium/Large, Color: Turkey Day Drumstick - Large
I have a small dog with a really strong bite! Usually have to buy toys that are meant for bigger dogs. This has lasted us for what feels like forever. It does sound very heavy when dropped! My dog loves it though! Would definitely recommend!
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Reviewed in the United States on May 2, 2026
★★★★★ 5
Crazy for her iguana!
Size: Medium/Large, Color: Illana the Iguana - Large, Size: Medium/Large, Color: Illana the Iguana - Large
Instant fav for my girl but looks like I'll be replacing often 🤪 she is a super chewer. She loves the soft vs hard combo on toys. Damage in the pic is within 10 mins. 😬😬😬 excellent quality
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Reviewed in the United States on May 27, 2026
★★★★★ 3
Foreign body risk for dinosaur dogs
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
My dog Bert had foreign body surgery 10 days ago because he swallowed a piece of a toy, so I was looking for something stronger, like for a tyrannosaurus rex. This toy had good reviews, so I bought it for him.
In 25 minutes and he'd chomped a chunk of the blue water part off. Bought the toy around 8am, gave it to him around 8pm, and it was in the trash by 8:30pm.
This toy is definitely NOT for super chewer tyrannosaurus rex dogs like Bert. But definitely IS a toy that is pretty sturdy and strong for dogs who don't have the bite force of a dinosaur.
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Reviewed in the United States on April 12, 2026
★★★★★ 4
Definitely not indestructable
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
I have a 1-year-old toy fox terrier (Rocky, pictured). He has been chewing on this toy for seven months now; it is one of his favorites. He has been unable to seriously damage the "ocean" portion of this toy, but as you can see from the provided image, the sea serpent has not faired that well. It is missing its snout and smaller portions of the humps. My guess is that the advertiser images showing much larger dogs with "like new" versions of the toy are just that...NEW AND UNCHEWED.
I have not had to clean up bits of this toy from my floor, so I assume Rocky has been swallowing them. My hope is that the yellow material of the serpent is not chemically dangerous when exposed to digestive fluids.
Rocky easily destroys plush toys in a matter of days if not hours and, consumed pieces of a small microfiber blanket that he liked to toss around and play tug-of-war with (past tense as he destroyed it and has since been trashed after I began finding feces-stained undigested pieces of it lying around). Since this toy has survived seven months and has remained recognizable, I have to agree it is durable.
Just beware, if my small toy fox terrier can damage the toy as pictured, expect your large breed chewer to do similar or worse damage. Also, the toy is very heavy! When Rocky drops it down a flight of stairs, it makes a MAJOR thud at the bottom, and sometimes makes me wonder if it might crack the large tile at the bottom.
I cautiously recommend the product.
Note the yellow frisbee in Rocky's picture. It is only a few months old and surprisingly has not suffered any chew damage despite substantial abuse. It appears to bend in the wind like a proverbial reed, evading damage by yielding to pressure.
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Reviewed in the United States on July 5, 2024
★★★★★ 5
Dog loves it! For tough chewers for sure
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
Dog absolutely loves it, he’s super rough on all of his toys they usually last about 10 minutes bore they are torn to shreds. It’s lasting through his chewing so I’m happy. It’s also super cute.
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Reviewed in the United States on April 9, 2026