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Description
The Deeper Genome: Why There Is More to the Human Genome Than Meets the EyeOver a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought just over 20,000, the same sort of number as a fruit fly or worm. What's more,
Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought -- just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportion of DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'? Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact of its 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes of Neanderthals as well as that of chimps about the development of our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.Binding Type: Paperback
Publisher: Oxford University Press, USA
Published: 10/24/2017
ISBN: 9780198813095
Pages: 400
Weight: 0.60lbs
Size: 7.60h x 5.00w x 0.90d
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Size: One Size, Color: (001) Black / Black / Reflective, Size: One Size, Color: (001) Black / Black / Reflective
This hat (visor) is by far one of the most comfortable ones I’ve ever worn! Absolutely love it!!!!
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Reviewed in the United States on May 18, 2026
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Underarmor
Size: One Size, Color: (001) Black / Black / Reflective
Me encanta todo lo de esta marca. Calidad
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Reviewed in the United States on June 2, 2026
★★★★★ 5
Great running visor
Size: One Size, Color: (541) Tux Purple / Pitch Gray / Reflective
Love love love this visor. Light weight and great to run in. Highly recommend
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Reviewed in the United States on September 1, 2025
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Perfect hat for shielding from the sun
Size: One Size, Color: (299) City Khaki / / Stone, Size: One Size, Color: (299) City Khaki / / Stone
Perfect hat for hot weather, it fits well and shields my face from the sun!
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Reviewed in the United States on August 19, 2025
★★★★★ 5
Great fit
Size: One Size, Color: (005) Black / White / White
Fits great. Not all caps fit women well, this one does.
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Reviewed in the United States on February 16, 2026