SKU: 74327397550

PDGFRAlpha (5D1) Mouse mAb

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Description

PDGFRAlpha (5D1) Mouse mAbPlatelet derived growth factor (PDGF) family proteins exist as several disulphide bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor Alpha (PDGFRAlpha) and PDGF receptor Beta (PDGFRBeta). PDGFRAlpha and PDGFRBeta can each form heterodimers with EGFR, which is also activated by PDGF. Various cells differ in the total number of

Platelet derived growth factor (PDGF) family proteins exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor Alpha (PDGFRAlpha) and PDGF receptor Beta (PDGFRBeta). PDGFRAlpha and PDGFRBeta can each form heterodimers with EGFR, which is also activated by PDGF. Various cells differ in the total number of receptors present and in the receptor subunit composition, which may account for responsive differences among cell types to PDGF binding. Ligand binding induces receptor dimerization and autophosphorylation, followed by binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules, such as GRB2, Src, GAP, PI3 kinase, PLCGamma, and NCK. A number of different signaling pathways are initiated by activated PDGF receptors and lead to control of cell growth, actin reorganization, migration, and differentiation.

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SKU: 74327397550

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ShelbbLC
Belleville, US
★★★★★ 3
Love the sheets but GOSH THEY STINK
Color: 19 - Forest Green, Size: Queen (20" X 30")
I have the dark green sheets and bought these for extra cases to match. I would give them 5 stars if it weren’t for the fact that they smell absolutely horrible. I am so surprised after reading reviews that more people don’t mention it?! Maybe it’s more prominent in darker colors but I have washed these now 3 different times even with scent beads and still hate the smell. I wish I could accurately describe what it smells like— it’s just not good and for some reason, body heat only exacerbates it and makes the smell even worse and I wake up feeling like a smell like the sheets… which isn’t a good thing. Besides that, I do really enjoy them. They feel great on your skin and I love the color. I wish the smell didn’t kill them so badly for me ☹️
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Reviewed in the United States on June 9, 2026
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Amy
Chelsea, US
★★★★★ 5
Comfy soft pillow covers
Color: 02 - White, Size: Queen (20" X 30"), Color: 02 - White, Size: Queen (20" X 30")
Absolutely love these pillow cases! I bought 2 sets. After I received them & washed & dried them they did remain wrinkly. I just went ahead and put them on my pillows & the wrinkles went away. I continue to love the feel, coolness & comfort. Will definitely buy more.
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Reviewed in the United States on April 5, 2026
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Lisa Brown
Houston, US
★★★★★ 5
Great soft pillow cases
Color: 03 - Navy, Size: Standard (20" X 26")
Pillow cases are beautiful and soft, great quality. I had to return them because standard were too small. I am going to order queen instead.
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Reviewed in the United States on June 9, 2026
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SadSushi
Los Angeles, US
★★★★★ 5
Comfortable
Size: Standard (Pack of 2), Style: Medium, Configuration: Hometextile
Fluffy and of good quality.
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Reviewed in the United States on May 1, 2026
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Isabella
Omaha, US
★★★★★ 5
Fluffines
Size: Standard (Pack of 2), Style: Medium, Configuration: Hometextile
I am very happy with this Down Alternative Pillow! It is soft, comfortable, and provides great support for my head and neck
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Reviewed in the United States on June 2, 2026

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