D-Lokus (d2)
SKU: 24642205719

D-Lokus (d2)

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Description

D-Lokus (d2)Der D Lokus ist verantwortlich fr die Verdnnung der Fellfarbe. Bekannte Mutationen des MLPH Gens (Melanophilin) sind verantwortlich fr die meisten Flle von verdnnten Farben. Das MLPH Gen kodiert fr ein Protein, Melanophilin, einen Schlsselbestandteil bei der Bildung von Haar und Hautpigmenten. Eine Mutation im Gen verursacht die unsachgeme Verteilung von Melanosomen und die Verdnnung der Fellfarbe. Es hat einen Einfluss auf die Bildung von schwarzem

Der D-Lokus ist verantwortlich für die Verdünnung der Fellfarbe. Bekannte Mutationen des MLPH-Gens (Melanophilin) sind verantwortlich für die meisten Fälle von verdünnten Farben. Das MLPH-Gen kodiert für ein Protein, Melanophilin, einen Schlüsselbestandteil bei der Bildung von Haar- und Hautpigmenten. Eine Mutation im Gen verursacht die unsachgemäße Verteilung von Melanosomen und die Verdünnung der Fellfarbe. Es hat einen Einfluss auf die Bildung von schwarzem Eumelanin sowie rotem-gelbem Pheomelanin, jedoch in geringerem Maße. Die Verdünnung des schwarzen Pigments führt zu blauer oder grauer Fellfarbe, und die Verdünnung des braunen Pigments führt zu hellbraun oder Isabella. Der D-Lokus ist nicht nur für die Verdünnung des Fellpigments verantwortlich, sondern verdünnt auch das Pigment der Nase, Pfoten und Augen.

In unserem Labor testen wir 3 verschiedene Allele im MLPH-Gen, die für die Verdünnung der Fellfarbe verantwortlich sind:

  • Allele d1: ist verantwortlich für die Verdünnung der Fellfarbe bei vielen Hunderassen

  • Allele d2: ist vorhanden bei Chow-Chow, Sloughi, Thai Ridgeback und Französischer Bulldogge

  • Allele d3: ist vorhanden bei Chihuahua, Mudi, Pumi, Italienischem Greyhound, Pekinese, Shetland Sheepdog, Shih Tzu, Tibetischem Mastiff und Yorkshire Terrier.

Bei einigen Hunderassen können mehrere verschiedene Mutationen gleichzeitig auftreten. Die Kombination von zwei Mutationen (d1/d2 oder d1/d3) führt ebenfalls zu einer verdünnten Fellfarbe.

Genotyp

Beschreibung

D/D:

Der Hund trägt zwei Kopien des dominanten D-Allels und zeigt eine normale, nicht verdünnte Fellfarbe; der Hund wird immer eine Kopie des D-Allels an die Nachkommen weitergeben; alle Nachkommen werden eine normale, nicht verdünnte Fellfarbe zeigen.

D/d*(d1 oder d2 oder d3):

Der Hund trägt eine Kopie des dominanten D-Allels und eine Kopie des rezessiven d-Allels; der Hund ist heterozygot/Träger des d-Allels für die Farbverdünnung und zeigt eine normale, nicht verdünnte Fellfarbe; die Nachkommen haben eine 50%ige Möglichkeit, das D-Allel zu erben, und eine 50%ige Möglichkeit, das d-Allel zu erben.

d*/d*(d1 oder d2 oder d3):

Der Hund trägt zwei Kopien des rezessiven d-Allels und zeigt eine verdünnte Fellfarbe; der Hund wird immer eine Kopie des d-Allels an die Nachkommen weitergeben.

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SKU: 24642205719

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BOBBY
Lexington, US
★★★★★ 5
Review
Scent: Casked Vanilla
I really like Cremo body wash. They have so many different scents. I have 5 of them. Choose the scent that best fits u..
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Reviewed in the United States on April 4, 2026
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Randy woodall
Belleville, US
★★★★★ 5
Choose your smell
Scent: Casked Vanilla, Scent: Casked Vanilla
It is very good body wash. I tried the Fragrance. It’s ok but I like the golden Amber much better. I also like the shampoo and conditioner
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Reviewed in the United States on May 31, 2026
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Colvinson Valeus
Lake Worth, US
★★★★★ 5
One of the best
Scent: Bourbon Oak
One of my go to and you won't regret it
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Reviewed in the United States on June 4, 2026
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Deebz
Charlottesville, US
★★★★★ 5
• Create a signature fragrance for a foaming dispenser
Scent: Palo Santo, Size: 16 Fl Oz (Pack of 2), Scent: Palo Santo, Size: 16 Fl Oz (Pack of 2)
One of the features that I enjoy about liquid soap is its ability to quickly refresh skin. This Palo Santo product is certainly one of the most unique offerings on the market; it is warm and pleasant, albeit a short-lasting fragrance as should be expected of any body wash. While most customers will consider using this product exclusively as a body wash, my preference is to enjoy it throughout the day as a hand and face refreshment. Use a foaming soap dispenser This product can be used as a daily hand and facial wash. Now, you might be thinking that this would be pretty inconvenient because the product is contained in a talI bottle with a flip-up top that can be both clumsy to use and takes up counter space. To address these problems, transfer the product into a small, foaming pump, counter top dispenser. Now I know what you’re thinking; how is this possible? This product has a viscosity similar to syrup. It will never pass through a foaming dispenser. And you would be correct in that critique; so don’t use it straight-up from the Cremo bottle. Instead, dilute the product with water. Since I’ve used this method before with other liquid soap products, I know that it will work consistently by following a few simple steps. The goal is to make a diluted solution of at least 90% warm water and 10% product, in other words a 9-to-1 dilution. Using a smaller ratio with too much product will likely jam the pumping mechanism because the product is too viscous to transit the foaming mechanism. How would this be done? Step 1. Select an empty foaming soap dispenser. The brand is not as important as long as you are able to fill it with water and soap product. Step 2. Fill the dispenser with warm water to reach about three inches from the top of the bottle. Step 3. Pour in Palo Santo to raise the water level to about one inch above the existing water line. Step 4. Cover the top of the dispenser with your palm and gently mix the product and water by rocking the bottle, or stir the product until it mixes with the water. I don’t recommend shaking the bottle. Shaking will result in a lot of soapy lather escaping the container before the pump top is reattached. Note: When filling the container, leave enough air space at the top of the dispenser for the stem and pump mechanism to be returned to the container. Overfilling just means that some product will escape when recapped. Step 5. After the top is reattached, prime the pump a few times and the foam mixture should smoothly leave the bottle. Photo One shows the water and Palo Santo mixture. As you can see, the mixture is transparent. The result is an easy to use hand and face foam wash. This pump spray approach means that the Cremo bottle can be stored away until a refill is needed. This process should work for every clear Cremo product. Create your signature fragrance The Palo Santo fragrance is unique, but its colorless appearance in a dispenser is not inviting. The product could use some color to make it more appealing and some zhoosh fragrance from another product. To accomplish this, add an extra body wash product that is both colorful and has a complementary fragrance to the original Palo Santo. All it takes is this addition to Step 3: Step 3-PLUS. Add about a quarter inch of another liquid soap to the container and mix it as in Step 4. The result is now a colorful mixture with a more expressive fragrance. Three different combinations In my first trial, Palo Santo was mixed with sage and cedar wood that added an attractive teal color (see photo 2). In the second trial Palo Santo was mixed with mint and rosemary making a blue combo (see photo 3). The third trial was a mixture of coconut and black pepper creating a purple mixture (see photo 4). Each of these combinations produced a complex blend of fragrances that would appeal to family and friends. Blend Palo Santo to your personal taste Palo Santo has a reputation for being a “mature” fragrance. Fair enough. But it does need to be—like Old Spice(y) or Hai Karate. Instead, it can be developed into a more chic and modern choice. By adding a dash of extra ingredients, you can design a blended Palo Santo fragrance that is both more complex and appealing. Certainly, with a little experimentation, you can also create a variety of mixtures that enhance Palo Santo and broaden the spectrum of your daily hand and face wash products. Just start with your favorite Cremo product and zhoosh-it-up.
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Reviewed in the United States on September 7, 2023
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Scott
Pawtucket, US
★★★★★ 5
Screamo for Creamo! Update on Sage and Citrus and Cologne
Scent: Bourbon Oak, Size: 16 Fl Oz (Pack of 2)
So first off the product came exactly as depicted. The smell was good but not strong or offensive. It has a pleasing woodsy smell. The name says it all. The lather is not particularly big but that doesn’t define how clean you get. I think it cleaned me up very well with one caveat. My face is a little oily so I did purchase the Creamo face wash. The body wash really didn’t do the trick for my face which is somewhat oily. The bottle is reminiscent of the past and stylish. It overall is a great product. I just bought the Sage and Citrus body wash. This is a great all season body wash with a more contemporary smell. It’s lighter than the Bourbon and Oak with, as stated, a citrus smell tempered with the earthy sage. Again it does not clean my oily face but I use the Creamo face wash and it does just fine. The rest of my body feels clean and the scent is light and not overpowering. Between both products I also use the shaving cream. I enjoy the original scent. I tried the Bourbon scent with the Bourbon and Oak body wash and felt it was a little overpowering. On a good note I combined all this with the Bourbon and Oak cologne. The shaving cream last a long time and should be used sparingly. The value is in the amount you use. It’s far less than a cheaper shaving cream but offers superior protection and excellent moisturizing elements. The cologne lasts all day and does not require but a single spray under both arms and a single spray on a wrist rubbed against the other. If you need an anti perspirant use one without a scent since this will conflict with the cologne. The value is definitely there as this cologne albeit simple in appearance has very delicate notes reminiscent of my more expensive cologne. I use Creed Vetiver for going out. This cologne has a very similar quality but is, of course, a different bouquet. Overall the whole line of Creamo products seems to be well thought out and outshines many higher end products such as Clinique or Brickell which I have also used. It comes down to value and quality. That’s where it really wins. It’s made in California where I live!
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Reviewed in the United States on August 23, 2019

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